In America and Europe, the everyday “food mushroom” is the common button mushroom (Agaricus bisporus), commercially cultivated in France since the 1600′s. In the Far East, however, the likewise centuries old cultivation of gourmet mushrooms has been primarily focused on an entirely different species – the Shiitake. Only in the last few decades has Shiitake become a common household name in the West.
Originating in China, wild Shiitake is also commonly known as Black Mushroom and Chinese Mushroom. The name Shiitake comes from the Chinese Shii Tree, which is the most common host tree. But it can also grow on beeches and oaks. The cultivation of Shiitake in China and Japan goes back at least 1000 years.
Although most westerners are now familiar with Shiitake as a food mushroom, few know that it’s also the most researched medicinal mushroom in Asia. As with other medicinal mushrooms, the research has largely focused on applications against cancer, [94] but also on its anti-viral properties. [93]
The preferred part of Shiitake to use medicinally is the mycelium (the “roots”) because they contain compounds that either don’t exist in the fruit body (“mushroom”), or are much more concentrated in the mycelium.
In fact, the most commonly researched Shiitake extract is known as Lentinula Edodes Mycelia extract, or LEM for short. (Lentinula edodes is the Latin name for Shiitake.) LEM has been reported in various research papers as being anti-bacterial, [98, 99] boosting the immune system, [95, 96, 97] and being anti-tumoral. [100] A study on melanoma found that it killed the mutated melanoma cells but caused no harm to cells that were healthy. [101]
Another active compound of Shiitake extract that has been much studied is Lentinan; a protein-free polysaccharide, so named after Lentinula, the Latin genus name for Shiitake. Lentinan does not directly kill tumors but has been shown to stimulate the tumor fighting mechanisms in the body of test subjects, [102, 103, 104, 105, 106, 107, 108, 109, 110] and is in fact in use in Asia as an injected cancer medication.
Arabinoxylanes of Shiitake extract derived from rice cultivated mycelium have been shown to have powerful anti-viral properties. [111, 112, 113]
Specifically herpes simplex virus type 1 [114] and more importantly HIV have responded to Shiitake extracts in several studies. [115, 116, 117] However, the previously mentioned Lentinan polysaccharide, by itself, has no significant effect on the replication of HIV. [25]
Furthermore, other studies have shown that Shiitake extract may be beneficial in the treatment of Candida, [118] chronic fatigue syndrome, [119] and to prevent septic shock. [120]
In his book Mycelium Running, medicinal mushroom expert Paul Stamets also lists the following areas where research has shown Shiitake extract to have a beneficial effect: Blood Pressure; Blood Sugar; Cholesterol; Kidney Tonic; Liver Tonic; Sexual Potentiator; Stress; Breast Cancer; Liver Cancer; Prostate Cancer. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.
Credit: Thank you to Paul Stamets for source material.
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